Pharmacology
The pharmacology of Edarbi involves its transformation from a prodrug to its active form, azilsartan, which acts as a selective angiotensin II receptor antagonist. Azilsartan helps in lowering blood pressure by preventing blood vessels from narrowing. It is advised to correct volume or salt depletion before administering Edarbi. The recommended dose for adults is 80 mg once daily, with a starting dose of 40 mg for patients on high diuretic doses. Additionally, Edarbi can be used alone or in combination with other antihypertensive agents. Consult with your healthcare provider for personalized dosage instructions based on your medical condition.
Dosage and Administration
When initiating Edarbi treatment, it is important to correct volume or salt depletion beforehand, or begin with a starting dose of 40 mg. The recommended dose for adults is 80 mg taken orally once daily. For patients already on high diuretic doses, a starting dose of 40 mg is considered. Edarbi can be taken with or without food depending on individual preference. It is advisable not to repack the medication but instead use it in its original container to protect it from light and moisture. Always follow your healthcare provider’s instructions for the best results.
Contraindications and Warnings
It is essential to correct volume or salt depletion before initiating Edarbi treatment or consider starting at a lower dose of 40 mg for certain patients. In case of hypotension, patients should be placed in a supine position, and if needed, given an intravenous infusion of normal saline. Close medical supervision is recommended to monitor and manage potential hypotensive episodes. Prioritize consulting with your healthcare provider regarding any concerns or side effects experienced while taking Edarbi.
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