Hydroxyurea acts by increasing the amount of HbF in the blood, preventing complications from sickle cell disease. This medication falls into the category of chemotherapy drugs, mainly used for treating certain types of leukemia, head and neck cancer, and sickle cell anemia.
Drug Class and Dosage Forms of Hydroxyurea
Hydroxyurea⁚ Mechanism of Action and Drug Class
Hydroxyurea acts by increasing the amount of HbF in the blood, preventing complications from sickle cell disease. This medication falls into the category of chemotherapy drugs, mainly used for treating certain types of leukemia, head and neck cancer, and sickle cell anemia.
Hydroxyurea Dosage Forms
Hydroxyurea is available in capsule form. The capsules come in various strengths, such as 200mg, 300mg, 400mg, and 500mg; Additionally, there are oral tablet formulations of hydroxyurea, with strengths like 100mg and 1000mg. The preferred dosage form may vary depending on the condition being treated and the patient’s specific needs.
Recommended Dosage and Administration
The dosage of hydroxyurea should be individualized based on factors like tumor type, disease state, patient risk factors, and response to treatment. Capsules are available in strengths of 500mg. For sickle cell anemia, the initial dose typically ranges around 15 mg per kilogram of body weight per day. Dosage adjustments may be made by the healthcare provider based on the patient’s condition.
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