Overview
Aggrenox is a medication approved by the FDA to lower the risk of stroke in individuals who have experienced a transient ischemic attack or ischemic stroke caused by a blood clot. This drug combines aspirin and extended-release dipyridamole, offering a more effective solution compared to using each medication individually. It is crucial to follow the recommended dosage and administration guidelines to maximize the benefits of Aggrenox while minimizing potential adverse effects. Consult with your healthcare provider for personalized recommendations based on your medical history and needs.
Indications
AGGRENOX is indicated for the prevention of stroke in patients who have had a previous stroke or transient ischemic attack (TIA). It is a combination antiplatelet agent designed to reduce the risk of stroke in individuals who have experienced transient ischemia of the brain or an ischemic stroke caused by thrombosis. It is essential to follow the prescribed dosage and administration instructions to achieve the intended therapeutic benefits. Consult with your healthcare provider for personalized recommendations based on your medical history and condition.
Dosage and Administration
It is essential to follow the prescribed dosage and administration instructions for Aggrenox diligently to ensure its effectiveness and minimize potential risks. Typically, Aggrenox is recommended to be taken as one capsule orally twice daily – once in the morning and once in the evening, with or without food. Swallow the capsules whole without chewing. In case of intolerable headaches during initial treatment, switching to one capsule at bedtime and low-dose aspirin in the morning can be considered, with a return to the regular regimen as soon as possible, usually within a week; Ensure consistent adherence to the prescribed regimen and consult your healthcare provider for any concerns or adjustments needed.
Contraindications and Warnings
It is crucial to be aware of the contraindications and warnings associated with Aggrenox to ensure safe usage and minimize risks. Aggrenox is contraindicated in patients with known hypersensitivity to any of its components. Aspirin, one of the components, should not be used in individuals with a known allergy to NSAIDs or conditions like asthma, rhinitis, and nasal polyps. Special caution is advised in patients with cardiovascular or GI diseases, bleeding disorders, history of peptic ulcer disease, or severe renal failure. The medication increases the risk of bleeding, and factors like concurrent use of anticoagulants or antiplatelet agents can further elevate this risk. Patients should be vigilant for signs of bleeding and gastrointestinal side effects and report any adverse reactions promptly to their healthcare provider.
Adverse Effects
It’s crucial to be aware of potential adverse effects that may arise while using Aggrenox. Some common adverse effects include stomach pain, heartburn, nausea, vomiting, gross gastrointestinal bleeding, and headaches, particularly during the initial treatment phase. Additionally, Aggrenox increases the risk of bleeding, especially when used concomitantly with other drugs that also elevate bleeding risk. Patients should promptly report any unusual symptoms, signs of bleeding, gastrointestinal discomfort, or severe headaches to their healthcare provider for further evaluation and management.
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