Active Ingredients
The transparent Contractubex Gel contains active ingredients that support the healing process inside the skin, regulating the production of scar tissue and working to positively influence scar formation. Contractubex contains three complementary active ingredients⁚ Extractum cepae, Heparin sodium, and Allantoin. Extractum cepae has anti-inflammatory and bactericidal properties, preventing the formation of excessive scar tissue, while Heparin sodium and Allantoin contribute to the healing process.
Mechanism of Action
While the exact mechanism of action of Contractubex Gel remains unknown, studies suggest that the silicone gel treatment affects the skin’s stratum corneum. The active ingredients in Contractubex Gel, including Extractum cepae, Heparin sodium, and Allantoin, work together to support the healing process, regulate scar tissue production, and influence scar formation positively. These ingredients may have anti-inflammatory, antibacterial, and healing properties that help prevent excessive scar tissue formation.
Application Instructions
The transparent Contractubex Gel is recommended to be gently massaged into the skin 2 to 3 times daily for a minimum of 3 months. It forms a discreet film that helps protect the sensitive scar tissue. Application should only be done on closed wounds, avoiding contact with eyes, nose, or mouth. Starting scar treatment early with Contractubex Gel can lead to more positive outcomes in scar reduction and healing.
Clinical Use
Contractubex Gel is commonly used in clinical practice for the treatment of hypertrophic scars and keloids. These types of scars are characterized by exaggerated extracellular matrix and collagen deposition. The active ingredients in Contractubex Gel, such as Extractum cepae, Heparin sodium, and Allantoin, work together to support the healing process and regulate scar tissue formation. Starting scar treatment early with Contractubex Gel can lead to positive outcomes in scar reduction and healing.
Preventative Effects
Contractubex Gel has shown preventative effects in reducing the formation of peritoneal adhesions. The gel’s combination of active ingredients, including onion extract (extractum cepae), sodium heparin, and allantoin, helps inhibit excessive connective tissue synthesis. This mechanism of action assists in reducing the number of re-laparotomies or re-laparoscopies caused by complications related to peritoneal adhesions. Early application of Contractubex Gel in a rat model of postoperative peritoneal adhesion (PPA) demonstrated a decrease in the amount of formed PPAs, highlighting its potential preventive impact.
Comparison with Other Treatments
Contractubex Gel, composed of active ingredients such as Extractum cepae, Heparin sodium, and Allantoin, offers advantages in reducing peritoneal adhesion formation. Studies suggest that Contractubex Gel may be effective in diminishing the amount of peritoneal adhesions formed, potentially reducing the need for additional surgical interventions like re-laparotomies or re-laparoscopies. This unique preventive effect sets Contractubex Gel apart from other treatments, showcasing its potential as a valuable option for addressing complications related to peritoneal adhesions.
Pharmacological Formulation
The pharmacological formulation of Contractubex Gel includes essential active ingredients that contribute to its therapeutic effects. One of the key ingredients is Extractum cepae, which provides anti-inflammatory and bactericidal properties, helping to prevent the formation of excessive scar tissue. Another vital component is Heparin sodium, which plays a role in the healing process. Allantoin, another active ingredient, also supports wound healing. The combination of these ingredients in Contractubex Gel offers a comprehensive approach to scar treatment and management.
Research Studies
Research studies have explored the efficacy of Contractubex Gel in various applications. In a study evaluating the effects of Contractubex Gel in a rat model of postoperative peritoneal adhesion (PPA), the results indicated that while a single dose did not prevent PPA formation, it did diminish the amount of formed PPAs. The study highlighted the potential of Contractubex Gel in reducing postoperative peritoneal adhesion-related complications. Further studies have focused on the anti-inflammatory and fibroblast proliferation-reducing effects of Contractubex, showcasing its therapeutic potential in scar treatment and management.
Side Effects and Dosage
Contractubex Gel has been reported to have very rare side effects, with occasional occurrences of skin reactions. The gel exerts antiproliferative, anti-inflammatory, softening, and smoothing actions on proliferating scar tissue. The recommended dosage typically involves gently massaging Contractubex Gel into the skin several times a day until the gel has been fully absorbed. Following the prescribed dosage instructions assists in maximizing the benefits of Contractubex Gel without significant adverse effects.
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