Overview of Hydroxychloroquine
Hydroxychloroquine (Plaquenil) is used to treat malaria, rheumatoid arthritis, and lupus. It can interact with over 400 medications٫ including gabapentin and metoprolol; It may cause side effects ranging from common issues like nausea and headache to more serious conditions like heart problems.
Interactions with Other Medications
Hydroxychloroquine can interact with a total of 462 medications, some of which include gabapentin, atorvastatin, and metoprolol. Additionally, it may have interactions with cimetidine, a medication used for stomach ulcers. These interactions can range from minor to major, so it’s important to consult with your healthcare provider before taking hydroxychloroquine alongside other drugs.
Warnings and Precautions
Hydroxychloroquine may cause serious side effects like changes in vision, heart problems, muscle weakness, and skin reactions. It is essential to be cautious if prolonged use is necessary, as it could lead to various health complications. Patients should be monitored regularly by a healthcare provider to minimize risks associated with the medication.
Long-Term Side Effects
If taking hydroxychloroquine for an extended period, your healthcare provider may monitor you for potential long-term side effects. Regular check-ups, including blood tests, eye examinations, and assessments of muscle function, are essential to detect any adverse effects early. Some long-term side effects may include changes in vision, muscle weakness, heart problems, and skin reactions. It’s crucial to follow up with your doctor to manage these risks.
Reporting of Adverse Events
From 1970 to Dec. 31, 2019, there were 24,728 adverse events related to hydroxychloroquine reported to the U.S. Food and Drug Administration’s Adverse Event Reporting System (FAERS). Among these cases, 20,713 were classified as serious, including 914 deaths. It’s important to note that these reports are voluntary, and the actual number of incidents may be higher as many side effects go unreported. The CDC considers hydroxychloroquine to be relatively well-tolerated, but monitoring and reporting adverse events to healthcare authorities remain crucial in ensuring medication safety.
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